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Description
Retatrutide a triple agonist of GLP-1, GIP, and glucagon receptors (half-life ~6 days), promoting insulin secretion, hepatic fat oxidation, appetite suppression, and energy expenditure
PBS listing depends on Eli Lilly applying for it and the Pharmaceutical Benefits Advisory Committee recommending it
Additionally, GLP-1 modulates the phosphorylation of AKT, ERK, GSK-3B, and mTOR to increase cell viability and growth (25, 26)
How to Decide: Discontinuation vs
