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New England Journal Of Medicine *In a 68-week placebo-controlled study of 1,961 obese and overweight non-diabetic adults with weight-related conditions, those on semaglutide lost on average 14.9% of their weight as opposed to 2% of the placebo group
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2 = 0.050), with slightly higher values observed in the semaglutide group compared with tirzepatide

Additionally, it enhances lipid metabolism, improving lipid profiles by lowering triglyceride levels and increasing HDL cholesterol