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Allegations against Novo Nordisk include that Wegovy (generic name semaglutide) causes gastrointestinal issues, vision loss (NAION), and now blood clot-related side effects, which the company does not properly warn patients about

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In one third of patients, two doses are required to cover the 24h period
PGC1 helps increase UCP1 gene activity by working with PPAR, leading to more UCP1 production [24]