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These findings help us understand how tirzepatide improves metabolic health and can guide the development of future treatments

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Someone with more adipose tissue at the injection site may absorb the medication slightly differently than someone with less

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Retatrutide may help reduce visceral fat, which is the deeper abdominal fat linked to insulin resistance and metabolic dysfunction

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The SURMOUNT-5 trial showed that maximum-dose tirzepatide produces about 47% more weight loss than maximum-dose semaglutide, so they are clearly not equivalent at their respective maximums

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