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J Cachexia Sarcopenia Muscle 13(2):919931 Lim C, Nunes EA, Currier BS, Mcleod JC, Thomas AC, Phillips SM (2022) an evidence-based narrative review of mechanisms of resistance exerciseinduced human skeletal muscle hypertrophy

Most patients require gradual dose escalation over 416 weeks to reach an effective level (typically 0.5 mg to 2.4 mg weekly)

GLP-1 RAs and naltrexone/bupropion have shown efficacy in attenuating hedonic drive through hypothalamic and mesolimbic modulation, offering therapeutic tools beyond caloric restriction [200]

Day Spacing: Monday/Thursday vs Other Combinations Monday and Thursday gives you a 3-day gap followed by a 4-day gap
