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Description
Piperazinopyrrolidine Analogs In a study by Ram Najar Kushwaha et al., a range of compounds was synthesized, among which 1-(2-(4-(7-chloro-4-quinolyl) piperazin-1-yl) acetyl) pyrrolidine (compound 23) was identified as a DPP-4 inhibitor (100)
Colesevelam, which requires a much lower quantity of drug because of its high affinity and binding capacity for bile salts, has less of an effect on the absorption of other drugs than other bile acid sequestrants but can still adversely affect the absorption of certain drugs (Table 30) (424)
Liu S, et al
FDA Drug Safety Communication
