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Common side effects of these so-called GLP-1 receptor agonists nausea, diarrhea, vomiting and constipation can be significant

The hallmarks of the Fontan circulation (and Fontan failure) are elevated central venous pressure and low cardiac output

This mechanism enhances glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows gastric emptying, which collectively improves glycemic control and promotes weight loss

The frequency of follow-up should be individualised based on your needs and clinical situation, but typically includes: Reviews every 3-6 months initially, then at least annually once stable Blood pressure and heart rate measurement at each visit HbA1c monitoring to assess glycaemic control Annual cardiovascular risk assessment Renal function and lipid profile monitoring If you have pre-existing diabetic retinopathy, appropriate eye monitoring is essential, as rapid improvements in blood glucose can temporarily worsen retinopathy
