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High blood sugar (hyperglycemia) and insulin resistance result from your bodys inability to produce, use, or make enough insulin, a pancreatic hormone that converts food into energy

10.1056/NEJMoa2032183 90 YangJ.RenJ.SongJ.LiuF.WuC.WangX.et al (2013)

The relationship between GLP-1 receptor agonists and reproductive hormones is complex and primarily indirect, mediated through improvements in metabolic health rather than direct hormonal modulation

Both anti-sense primers were used with the same sense primer