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is Del Nido cardioplegia, originally developed for pediatric myocardium Delivery strategies include: Antegrade (via aortic root) standard approach Ostial (direct coronary delivery) used when aortic root cannot be relied upon Retrograde (via coronary sinus) useful in severe AI or coronary disease NOTE: Severe aortic regurgitation can impair antegrade delivery and requires alternative strategies and LV venting What do cross-clamp time and bypass time represent clinically

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Incidence rates of 3-point MACE were 30.3 and 40.0 events per 1000 person-years for OW semaglutide and dulaglutide, respectively