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Endocrinology 1998 139 2811-2817

D-amino acid substitutions have been used in several applications, including development of antimicrobial peptides, improvement of the enzymatic stability, enhancement of the antiangiogenic activity and anticancer action, assistance of the metal-based peptide bond hydrolysis and control of the peptide hydrogel degradation in cells

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The structure was refined using Phenix 31 and Buster 32 with manual examinations of 2Fo-Fc and Fo-Fc maps with Coot 33
