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It was evident that retatrutide showed clinically meaningful improvements in glycaemic control and impressive reductions in body weight in type 2 diabetic patients while being relatively safe

There have been isolated post-marketing reports of cardiac rhythm disturbances in patients taking GLP-1 receptor agonists, though a causal relationship has not been established

Bone density improvements, which require longer remodeling processes, may take 6 months to a year

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