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Risk Stratification & Contraindications Patient safety must guide the initiation of GLP-1 therapy, and therapy should be withheld if contraindications are present: Absolute Contraindications: Personal or family history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Cautionary History: Previous pancreatitis or gastroparesis 5

Fibrosis stage matters because it helps estimate future risk

Try: 20 ounces before breakfast 20 ounces before lunch 20 ounces before dinner Additional water throughout the day Simple systems usually outperform willpower

[DOI] [PMC free article] [PubMed] [Google Scholar] 537.Teta M., Long S.Y., Wartschow L.M., Rankin M.M., Kushner J.A