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Wait at least 30 minutes before eating, drinking anything else, or taking any other tablets or supplements

This process also stimulates collagen production, which can help tighten skin and reduce the appearance of loose or sagging skin

Some patients also report reduced food intake leading to lower core body temperature throughout the day

In the SURMOUNT-1 trial, tirzepatide produced dose-dependent weight reductions, with average losses approaching or exceeding ~20% at higher doses in adults with obesity who did not have diabetes, numbers that markedly exceed historical pharmacotherapy benchmarks