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All animal experiments were approved by the Institutional Animal Care and Use Committee of Xinhua Hospital affiliated with Shanghai Jiao Tong University School of Medicine and were conducted in accordance with Guide for the Care and Use of Laboratory Animals (National Research Council 1996, USA)

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Next, the drugs exenatide (Byetta) and liraglutide (Victoza and Saxenda) were developed

However, Ozempic generally produces greater A1C reduction and more significant weight loss in comparison studies