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These approaches encompass nonoperative interventionsincluding dietary modification, exercise optimization, and pharmacotherapyas well as metabolic and bariatric surgical options within a synchronized multidisciplinary framework

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However, many of those who could benefit from these drugs are in lower income households and with the monthly cost as high as $1k without coverage, these drugs are out of reach for many who need it

Total fat mass was shown to have decreased by 20% over placebo, whereas lean mass increased by 4.4% over placebo, in bimagrumab treated patients after 48 weeks