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It is important to note that baseline HbA 1c was 6.4% in both groups which is below the American Diabetes Association (ADA) target for good glycemic control
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Sulfonylurea drugs affect sulfonylurea receptor 1 (SUR 1), which leads to the closure of adenosine triphosphate (ATP)-dependent potassium channels, preventing potassium from leaving the cell and depolarizing the cell membrane, leading to an influx of calcium and triggering insulin release
