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Description
The central application of GLP-1 receptor agonists potently decreases food intake, likely through GLP-1 receptor (GLP-1R)-expressing targets in multiple brain areas including in the hypothalamus and brainstem (24, 26, 28-30), nuclei also targeted by estrogen (31), supporting a potential interaction

GLP-1 helps with satiety, but the mindful practice amplifies it

Preserving it is essential to maintaining a healthy resting metabolic rate and long-term weight stability

By adding glucagon to the GLP-1 and GIP mix, the triple agonist approach essentially revs the engine, leading to a consistent spike in resting heart rate
