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Description
Semaglutide alone achieved 10-22% weight loss in STEP trials, while phentermine produces 5-8% loss before tolerance develops
As a GIP and GLP-1 receptor agonist, it is implemented as a second-line defense against type 2 diabetes for glycemic control and significantly reduces body weight
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In contrast, low-alcohol consuming rats show little change in their alcohol drinking after GLP-1R stimulation
