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Interestingly, the DPP-4 level has been found to correlate with levels of advanced glycation end products (AGEs), derived from nonenzymatic reaction between reducing sugars and amino groups of proteins, lipids, and nucleic acids, and related to chronic hyperglycemia and uncontrolled T2D

While these are not directly linked to kidney damage, dehydration (from nausea, vomiting or diarrhea) can worsen kidney function in some individuals

The Friday evening approach also aligns well with the pharmacokinetics of most GLP-1 medications

This formulation is available as mini troches (oral tablets) rather than injectable, starting at approximately $4 per troche