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Subsequently, the phosphorylated SHP2 together with its adapter molecule growth factor receptor-bound protein 2 (Grb2) activates the downstream ERK signaling cascades, inducing thermogenesis by controlling sympathetic activity on BAT, and promoting the anorectic effects of leptin [136, 137]

has participated in educational speaker meetings for Lundbeck, Otsuka, Sunovion, Janssen, Schwabe Pharma, ROVI Biotech and Recordati

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The role of adjunctive exenatide therapy in pediatric type 1 diabetes