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Description
It is composed of two domains, one transmembrane (TMD) domain that binds the N-terminal region of GLP-1 and the extracellular (ECD) that binds the C-terminal helix of GLP-1

Additionally, semaglutide acts on regions of the brain responsible for appetite regulation, thereby reducing hunger and food intake

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State health plan overseers voted Thursday to eliminate coverage for GLP-1 drugs for obesity, capping off months of torn decision-making over how to tamp down surging health care costs while maintaining care access for members
