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Published meta-analyses show berberine reduces fasting blood glucose by roughly 1015 mg/dL and HbA1c by 0.50.6% in people with type 2 diabetes or metabolic syndrome (Liang et al., 2019
Regardless of whether this very optimistic statement is true, what is true is that these drugs are effective for most patients who are obese in causing significant BMI reductions that previously would only be achievable with gastric bypass or sleeve gastrectomy

The Importance of Being Proactive Being proactive about your health means taking an active role in your treatment

Research published in NCBI analyzed FDA adverse event reports and human data, finding no firm evidence for increased pancreatic or thyroid cancer risk