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It is also worth mentioning that this study included participants with a BMI lower than recommended for this molecule in people without diabetes, and this might influence the generalizability of the results

Employing HITI for in vivo knock-in of large DNA fragments, we designed a guide RNA (gRNA) targeting exon 14 of the Alb gene (sgAlb-E14), which has demonstrated efficient ectopic gene integration via genome editing 20

[DOI] [PMC free article] [PubMed] [Google Scholar] 92.Luna-Marco C., de Maraon A.M., Hermo-Argibay A., Rodriguez-Hernandez Y., Hermenejildo J., Fernandez-Reyes M., Apostolova N., Vila J., Sola E., Morillas C., et al

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