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but the glucose-lowering effect of SGLT2is is limited 14

5.2 Potential Risks and Contraindications While Semaglutide has demonstrated efficacy in improving glycemic control, promoting weight loss, and reducing cardiovascular risk factors in individuals with type 2 diabetes and obesity, certain populations may be at increased risk of adverse events or may have contraindications to Semaglutide therapy

No statistically significant associations were found for other events (Table 4)

Muscle mass decreased by only 10% from baseline, accompanied by measurable improvement in intramuscular fat content
