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Description
According to the European guidelines (EASL-EASD-EASO), pioglitazone may be used in the treatment of NAFLD/MASLD in individuals with type 2 diabetes (off-label in those without type 2 diabetes)

Because the two act on separate receptors, combining them is intended to stimulate the GH axis from two angles at once

This drug slows digestion and changes how the body processes food, potentially leading to gut flora or mucus production changes

Decreased hippocampus volume and hippocampus atrophy are related to depressive episodes in patients affected by depression
