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Description
"Nothing was budging," Rossum said in a TODAY segment that aired on Nov
It is a dual GIP/GLP-1 receptor agonist, meaning it activates two incretin pathways simultaneously
Semaglutide plus bimagrumab produced the largest reductions in eWAT, iWAT, and rpWAT size, with greater than 60 % reductions in tissue weights relative to control animals (Figure 2A,B)
the small-molecule world will look to do the same, but likely as fixed-dose combinations of two or three orals rather than as single multi-functional peptides until true dual and triple small-molecule agonists can be found
