glp 1 when did it come out you know? #GLP1 medications have been around since 2005. 💊 GLP1 medications are safe The Evolution of GLP-1 Users

According to the FDA's press release it agreed to approve the drug for obesity based on three randomised, double-blind, placebo-controlled trials during which more than 2,600 patients received Wegovy for up to 68 weeks and more than 1,500 patients received placebo (US FDA 2021)

[DOI] [PubMed] [Google Scholar] 246.Bolli G.B., et al

If you recently started semaglutide or just moved to a higher dose, the symptoms you are experiencing may be entirely normal and unrelated to injection depth

Time was annualized and included as continuous along with the treatment effect (intercept) and an interaction between time and treatment (slope)