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PLoS ONE 18(8 August):120 (2016) Liraglutide and cardiovascular outcomes in type 2 diabetes

[3] Dosing follows a monthly escalation schedule designed to minimize GI side effects: 0.8 mg 2.5 mg 5.5 mg 9 mg 14.5 mg 17.2 mg, with the target maintenance dose reached after about six months

The supramammillary nucleus, located in the hypothalamus, is a new candidate that appears to be responsible for GLP-1 mediated anxiety effects because selective activation of GLP-1Rs in this nucleus by exendin-4 resulted in intensified anxiety-like behavior both in male and female rats

[DOI] [PubMed] [Google Scholar] 110.Exenatide once weekly SPC
