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A dedicated phase 2a substudy in people with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) used MRI to measure liver fat and found that, after 24 weeks, retatrutide reduced relative liver-fat content by about 81% at the 8 mg dose and about 82% at 12 mg, versus essentially no change on placebo

As weight decreases, patients often find themselves enjoying increased energy and improved mobility, making it easier to embrace an active lifestyle
Medications Avoid and adjust medications known to cause dry mouth during cancer treatments when possible
