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[80] were able to show how both topical and systemic liraglutide administration prevented retinal degeneration in db/db mice
11 Exenatide has been associated with hypoglycemia when given in combination with metformin, SUs, and TZDs
The guidelines suggest initiating lifestyle interventions in combination with metformin at the time of diagnosis ( Figure 3 )
A 2023 retrospective cohort analysis in JAMA Internal Medicine (N=16,922) found that patients on a GLP-1 RA plus an opioid had a 33% higher rate of bowel obstruction-related ED visits compared to patients on a GLP-1 RA alone [5]
