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This study demonstrated that metformin increases circulating GDF15, which is necessary for its effects on energy balance and body weight

A new dosage or potency A new drug combination, such as semaglutide mixed with vitamin B12 A new drug form, such as a liquid or pill rather than an injection Brunner thinks clinicians will increasingly take advantage of these exceptions: I think we'll see more prescribers move into the customized dosage side of compounding. Custom Dosages This customization has also fueled interest in microdosing GLP-1s, a technique in which patients take smaller amounts to try to achieve gradual weight loss or minimize side effects

Low-sugar fruits: Berries (particularly raspberries with 6.5g fibre per 100g), apples, and pears offer sweetness with fibre and antioxidants