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Mechanisms of -Synuclein induced synaptopathy in parkinsons disease
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17,19 In contrast to other lipidated analogues studied, semaglutide-Am, GLP-1-Am (20, PEG2-PEG2--Glu-stear), which has a different spacer and lipid moiety attached, was shown to be present in solution mostly in the form of a single stable oligomer (Figure 3D,F)

This complication occurred despite the absence of other medications known to impair gastrointestinal motility, strengthening the temporal association with semaglutide [14]
