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Description
The first is that Eli Lilly was expecting greater non-diabetic weight loss with orforglipron based on phase 2 trials, and that apparently never happened for reasons that are still unclear

Avoid repeated freeze-thaw cycles to maintain peptide integrity
About 3% to 6% of people using Mounjaro or Zepbound will have some sort of reaction

That drove patients to seek out alternatives from compounding pharmacies, which, during shortages, can create their own versions of medications that do not have to be approved by the F.D.A
