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Based on the annualized event rates in the semaglutide and placebo groups, the SOUL trial was calculated to accumulate 1225 events at the end of 3.78 years, resulting in premature termination (Fig

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Food and Drug Administration (FDA), the approved dosages for some of the commonly prescribed GLP-1 agonists are as follows: Semaglutide (Ozempic): 0.5 mg, 1 mg, or 2 mg once weekly for type 2 diabetes, and up to 2.4 mg once weekly for chronic weight management (marketed as Wegovy)