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Patients with the following conditions should avoid FDA-approved semaglutide products: Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Severe allergic reactions to semaglutide History of pancreatitis Diabetic retinopathy Kidney problems Serious stomach issues Pregnancy or breastfeeding Compounded semaglutide , lacking FDA approval, does not have the same established safety guidelines or defined patient populations

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Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, De Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L (2015) Interventions to slow aging in humans: are we ready

Side Effects: What to Expect With Each Medication Lets stop pretending these are side-effect-free