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Sattar et al

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These longer-acting GLP-1R mimetics elicit more favourable cardiovascular outcomes than shorter-acting agents like exenatide or its analogue lixisenatide (EXSCEL and ELIXA), which demonstrated non-inferiority, but no obvious cardiovascular benefit [(64, 119, 148)
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For detailed information on how quickly semaglutide produces results , understand that therapeutic effects begin even at lower starting doses
