which has more side effects semaglutide or tirzepatide Comparative safety and of and tirzepatide: Implications for clinical decision-making in obesity management Tirzepatide vs. Semaglutide: Which Weight

Over-the-counter stool softeners like docusate sodium (100mg twice daily) or polyethylene glycol can provide relief within 12-72 hours when dietary changes aren't sufficient

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NICE recommends lifestyle and dietary support alongside GLP-1 treatment (NICE NG28), with patients benefiting from comprehensive dietary counselling to optimise treatment outcomes and minimise side effects

Cardiovascular outcome trials show that treatment with long-acting GLP-1 medicines such as liraglutide, dulaglutide, and semaglutide reduces cardiovascular events in people living with T2D and with semaglutide also in people living with obesity (6062)