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Mice receiving SG ran significantly less distance than their baseline (17093 970 wheel turns, t=17.624, p 81 s) bouts per day (Figure 5L-M, pooled sexes)

For example, the mean percent body weight reduction at Week 72 for late responders was 8.3%, 11.4% and 13.6% for 5, 10 and 15 mg, respectively

Understanding the distinction between direct pharmacological effects and indirect consequences of treatment is essential for informed clinical decision-making

We saw a rise when bariatric surgery became popular several decades ago, but things really tapered off until around two or three years ago when the GLP-1 rise occurred, Lee said