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Experimental drugs emerging as the next challenge One of the clearest trends in the March and April 2026 data was the appearance of unapproved, investigational obesity and diabetes drugs quietly entering the country under the generic antidiabetics n.e.c (not elsewhere classified) product code

Some potential side effects include: Diarrhea Constipation Nausea Heartburn Headaches Many of these symptoms resolve once your body adjusts to the medication

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Yet, there was no significant change in first-phase insulin secretion or insulin sensitivity by clamp studies (122)