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Description
Within the hypothalamus, Gipr- expressing cells are localized in the paraventricular, dorsomedial and arcuate nuclei and colocalize with markers for neurons, glia and vascular cells
Discussion The neuropsychiatric safety of GLP-1RAs has garnered attention, primarily owing to their centrally acting appetite-suppressing activity [Reference ONeil, Aroda, Astrup, Kushner, Lau and Wadden7]
It is important to note that higher-dose semaglutide (2.4 mg, marketed as Wegovy) is licensed specifically for weight management in obesity and has separate eligibility criteria and dosing from the diabetes indication
Bejleri, D
