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showed that the administration of the SGLT2i empagliflozin for 4 weeks, (compared to a control group), reduced fat mass, leading to morphological changes in adipose tissue, specifically an increase in the number of small and medium-sized adipocytes and a reduction in the number of large adipocytes [82], an indirect sign of browning [25]
All laxatives work in different ways, each with the intention of helping relieve constipation
The GLP-1 receptor agonist exendin-4 is one of the agents used in the treatment of type 2 diabetes [146] and is a long-acting receptor agonist of GLP-1 that also produces weight loss [147-149]
