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N Engl J Med 390(15):13941407

The two incretins identified in humans, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are primarily released from the ileum and jejunum, respectively

29 This period should be viewed not just as a time for the medication to induce weight loss, but as an active learning phase

However, both medications do not target glucagon (GCG) receptor (GCGR)