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GLP-1 may exert its effects locally via the vagus nerve before being degraded by DPP-4 in circulation

Early studies suggest that GLP-1 medicines do not appear to increase lupus flares in most people studied , and they may even be linked with better kidney and heart outcomes in some patients with lupus and type 2 diabetes

And his study showed that HRV reductions were statistically significant as early as four weeks

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