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However, an empty mouth is essential

All the above-mentioned mechanisms by which GLP-1 induces insulin sensitivity are presented in Figure 6

Individual tolerance to GLP-1s varies but the most common side effects are nausea, diarrhea, vomiting, constipation, stomach (abdomen) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn, and runny nose or sore throat

A study shows that when used with lifestyle changes, the weekly 2.4 mg dose of semaglutide reduced 10-15% of body weight compared to the placebo, which reduced body weight by only 2-3%