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Titration protocol and lab requirements not published

While not officially listed as a common side effect, this "emotional blunting" is part of how the drugs can lead to reduced food noise, as well as reduced alcohol or other drug urges, but at the same time may also result in diminished enjoyment in hobbies, competitive drive, even for some people loss of interest in exercising, as well as people describing a "loss of empathy" - though I also see it said that it is a temporary experience for some people

Oral glucose absorption induces GLP-1 (7-36)-amide release from intestinal L-cells into intestinal capillaries

Because semaglutide and tirzepatide are large peptide molecules, theoretical transfer is likely minimal, but definitive data does not exist