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Because systemic hormone therapy involves supplying the body with estrogen, its often not an option for women who have a history of or are at high risk for certain cancers or blood clots

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[DOI] [PubMed] [Google Scholar] Dillon JS, Lu M, Bowen S, Homan LL

Tamborlane WV, Barrientos-Perez M, Fainberg U, et al