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Description
Although chronic intracerebroventricular infusion of native LEAP2 decreases body weight and ghrelin-induced weight gain [30, 90], these findings should primarily be considered proof-of-concept pharmacological effects, as the physiological relevance of endogenous central LEAP2 signalling remains uncertain
Extended half-life via acylation
Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
Besides, an improvement in various profiles such as those of BMI, diastolic blood pressure, levels of CRP, lipid profile and HBA1c were observed
