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doi: 10.1007/s00125-009-1643-x 37 LiuGMaHQiuLLiLCaoYMaJet al
In addition, AMPK, through activation of FOXO1, can regulate transcription factor forkhead box protein 3 (FOXP3), the key gene for differentiation and homeostasis of T regulators lymphocytes (Tregs) presenting immunoregulatory and anti-inflammatory effects [202,206]
Similarly, the dose escalation also depends on your tolerability
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