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Conclusions Together our results suggest that liraglutide exhibits anti-inflammatory activity through the activation of the PKA/CREB pathway in an OA rat model.

This contrasts with conventional T2D therapies like sulphonylureas, insulin and thiazolidinediones, which induce weight gain as a by-product of treatment

As a physician who prescribes GLP-1 medications like Ozempic, Wegovy, semaglutide, and tirzepatide, I explain why increasing your dose too quickly can affect muscle mass, metabolism, and long-term metabolic health.

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