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19,20 Amarasate has been available for over 5 years in NZ, where there have been anecdotal reports of weight loss up to 60 lbs

These findings align with those of pooled analyses from liraglutide phase 2/3 trials in obesity171 and retrospective case-control studies in T2DM.172 It should be noted, however, that patients in the latter study did not receive high-dose GLP-1RAs approved for obesity and that detecting mental health disorders in routine clinical practice remains challenging

Similar discrepancy is observed in meta-analyses

Typically, patients of our weight loss program in Los Angeles, California who start FDA-approved GLP-1 medications like Ozempic and Wegovy lose an average 15% of their weight when combined with diet and exercise